abstract：:The present research work was designed to develop dorzolamide-loaded chitosan-coated polycaprolactone nanoparticles (DRZ-CS-PCL-NPs) for improved ocular delivery. The nanoparticles were prepared by single-step emulsification technique and optimized using the three-factor three-level Box-Behnken design. The optimized D...

journal_title：International journal of biological macromolecules

authors： Shahab MS,Rizwanullah M,Alshehri S,Imam SS

更新日期：2020-11-15 00:00:00

abstract：:The structure and molecular dynamics of α-L-arabinofuranosidase (PsGH43_12) of family 43 glycoside hydrolase, subfamily 12 from Pseudopedobacter saltans were studied. The modeled PsGH43_12 structure displayed 5-bladed β-propeller fold at N-terminal and β-sandwich fold at C terminal. Ramachandran plot showed 95.7% resi...

journal_title：International journal of biological macromolecules

authors： Thakur A,Sharma K,Jaiswal K,Goyal A

更新日期：2020-11-15 00:00:00

abstract：:Fibrinolytic enzymes are proteases responsible for cleavage of fibrin mesh in thrombus clots, which are the primary causative agents in cardiovascular diseases. Developing safe, effective and cheap thrombolytic agents are important for prevention and cure of thrombosis. Although a wide variety of sources have been dis...

journal_title：International journal of biological macromolecules

authors： Moula Ali AM,Bavisetty SCB

更新日期：2020-11-15 00:00:00

abstract：:We report the preparation of both control chitosan and magnetic chitosan beads as biosorbents using chitosan as matrix and magnetite (Fe3O4) nanoparticles as reinforcement followed by detailed advanced characterization. The batch trials were performed to study the adsorption kinetics of biosorbents by removing As(III)...

journal_title：International journal of biological macromolecules

authors： Ayub A,Raza ZA,Majeed MI,Tariq MR,Irfan A

更新日期：2020-11-15 00:00:00

abstract：:Two exopolysaccharides, NPS and APS, were isolated from L. plantarum WLPL09 and purified by ion-exchange chromatography. The structural analyses showed that molecular weight of NPS and APS were 72.60 kDa and 33.22 kDa, respectively. NPS was mainly composed of mannose and glucose, in molar ratio of 85.35:14.65, while A...

journal_title：International journal of biological macromolecules

authors： Jiang B,Tian L,Huang X,Liu Z,Jia K,Wei H,Tao X

更新日期：2020-11-15 00:00:00

abstract：:Although ginsenoside Rb1 (G-Rb1) has exerted an inhibitory effect on renal fibrosis and progression of chronic kidney disease (CKD), its mechanism remains unknown. This study aims to explore the anti-fibrosis effect of G-Rb1 in unilateral ureter obstruction (UUO) mouse model and underlying mechanisms in HBSS-induced H...

journal_title：International journal of biological macromolecules

authors： Liu X,Chen J,Sun N,Li N,Zhang Z,Zheng T,Li Z

更新日期：2020-11-15 00:00:00

abstract：:Silk is spun from the liquid precursor known as liquid silk secreted from the posterior part and stored in the silk gland lumen with occurrence of many momentary events. The liquid silk in the silk gland is transformed to the spun silk fibre. In this study the elucidation of the protein components of liquid silk from ...

journal_title：International journal of biological macromolecules

authors： Goswami A,Goswami N,Bhattacharya A,Borah P,Devi D

更新日期：2020-11-15 00:00:00

abstract：:Novel α-aminophosphonates 4 were synthesized via one pot three-component reaction of 4-aminoantipyrine, aldehydes, triphenylphosphite and Lewis acid catalyst. The chemical structures of all the synthesized compounds were elucidated by IR, NMR and MS spectral analysis. The antimicrobial activity of 4 was tested in vitr...

journal_title：International journal of biological macromolecules

authors： Elsherbiny DA,Abdelgawad AM,El-Naggar ME,El-Sherbiny RA,El-Rafie MH,El-Sayed IE

更新日期：2020-11-15 00:00:00

abstract：:Lectins are a group of widely distributed and structurally heterogeneous proteins of nonimmune origin. These proteins have the ability to interact with glycans present on cell surfaces and elicit diverse biological activities. Machaerium acutifolium lectin (MaL) is an N-acetyl-D-glucosamine-binding lectin that exhibit...

journal_title：International journal of biological macromolecules

authors： Dias LP,Santos ALE,Araújo NMS,Silva RRS,Santos MHC,Roma RR,Rocha BAM,Oliveira JTA,Teixeira CS

更新日期：2020-11-15 00:00:00

abstract：:Agrofood byproducts may be exploited as a source of biomolecules suitable for developing bioplastic materials. In this work, the feasibility of using starch, oil, and waxes recovered from potato chips byproducts for films production was studied. The recovered potato starch-rich fraction (RPS) contained an amylopectin/...

journal_title：International journal of biological macromolecules

authors： Gonçalves I,Lopes J,Barra A,Hernández D,Nunes C,Kapusniak K,Kapusniak J,Evtyugin DV,Lopes da Silva JA,Ferreira P,Coimbra MA

更新日期：2020-11-15 00:00:00

abstract：:The polysaccharides (CSPw, CSPc, CSPa, and CSPu) were prepared by hot water extraction, acid-assisted extraction, alkaline-assisted extraction, and ultrasound-assisted extraction from corn silk, respectively. High performance gel permeation chromatography (HPGPC), fourier-transform infrared (FT-IR) spectroscopy, and s...

journal_title：International journal of biological macromolecules

authors： Jia Y,Gao X,Xue Z,Wang Y,Lu Y,Zhang M,Panichayupakaranant P,Chen H

更新日期：2020-11-15 00:00:00

abstract：:Cranberry proanthocyanidin-chitosan nanoparticles (PAC-CHT NPs) loaded with antibiotic gentamicin (GEN) (PAC-CHT-GEN NPs) were formulated and characterized according to size, polydispersity (PDI), surface charge, morphology, and encapsulation efficiency (EE). PAC-CHT-GEN NPs were evaluated for their ability to aggluti...

journal_title：International journal of biological macromolecules

authors： Alfaro-Viquez E,Esquivel-Alvarado D,Madrigal-Carballo S,Krueger CG,Reed JD

更新日期：2020-11-01 00:00:00

abstract：:The fungal α-glucan synthases (Agss) are multi-domain proteins catalyzing biosynthesis of cell wall α-1,3-glucan which determines cell wall integrity or fungal pathogenicity and pullulan which is a maltotriosyl polymer made of α-1,4 and α-1,6 bound glucose units. The Agss family can be divided into 11 groups, some of ...

journal_title：International journal of biological macromolecules

authors： Qi CY,Jia SL,Wei X,Yang G,Chi Z,Liu GL,Hu Z,Chi ZM

更新日期：2020-11-01 00:00:00

abstract：:Oxidative stress plays a critical role in the progression of myocardial injury. Increasing evidence suggests that hiruidin can treat patients with cardio-injury. However, the mechanism of hirudin against myocardial infraction remains unknown. In the present study, we evaluated the potential role and mechanism of hirud...

journal_title：International journal of biological macromolecules

authors： Zhang H,Chen H,Li J,Bian Y,Song Y,Li Z,He F,Liu S,Tsai Y

更新日期：2020-11-01 00:00:00

abstract：:The development of thermosensitive smart hydrogels with suitable thermosensitivity is of great importance for various biomedical and pharmaceutical applications. In this study, thermosensitive chitosan/carboxymethylcellulose/scleroglucan/montmorillonite (CHT/CMC/SGL/MMT) nanocomposite hydrogels were prepared for biome...

journal_title：International journal of biological macromolecules

authors： Bozoğlan BK,Duman O,Tunç S

更新日期：2020-11-01 00:00:00

abstract：:Despite the progress in the development of hemostatic products, efficient treatment solutions to control hemorrhage upon wounding are still necessary. Chitosan (CS) is a natural hydrogel-forming polysaccharide, easy to modify for specific applications. Inorganic compounds in turn possess documented hemostatic properti...

journal_title：International journal of biological macromolecules

authors： Koumentakou I,Terzopoulou Z,Michopoulou A,Kalafatakis I,Theodorakis K,Tzetzis D,Bikiaris D

更新日期：2020-11-01 00:00:00

abstract：:One popular and relevant proposed function for cyanobacterial hemoglobin (Synechocystis Hb) is anaerobic nitrite reductase in vivo. During such reduction reactions, the hexacoordinated heme iron atom of SynHb is oxidized from the ferrous (Fe+2) to ferric (Fe+3) state and prevent damage by limiting the concentration of...

journal_title：International journal of biological macromolecules

authors： Uppal S,Khan MA,Kundu S

更新日期：2020-11-01 00:00:00

abstract：:The aim of the paper was to investigate the ability of an eco-friendly luminescent xerogel prepared by chitosan crosslinking with a phenothiazine luminogen to detect and remove heavy metals. Its ability to give a divergent morphological and optical response towards fifteen environmental relevant metals was investigate...

journal_title：International journal of biological macromolecules

authors： Bejan A,Doroftei F,Cheng X,Marin L

更新日期：2020-11-01 00:00:00

abstract：:Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. This paper briefly describes the source, properties, structure and application of sodium alginate by summarizing and analyzing the current ...

journal_title：International journal of biological macromolecules

authors： Guo X,Wang Y,Qin Y,Shen P,Peng Q

更新日期：2020-11-01 00:00:00

abstract：:Due to the problems raised by the use of animal or microbial recombinant proteases, the use of proteases from vegetable origin is becoming increasingly popular.. Among them, sulfidryl proteases have a special interest. Ficin is an outstanding example of this kind of proteases. This paper aims to be to make a comprehen...

journal_title：International journal of biological macromolecules

authors： Morellon-Sterling R,El-Siar H,Tavano OL,Berenguer-Murcia Á,Fernández-Lafuente R

更新日期：2020-11-01 00:00:00

abstract：:Failure of bioengineered meniscus implant after transplantation is a major concern owing to mechanical failure, lack of chondrogenic capability and patient specific design. In this article, we have, for the first time, fabricated a 3D printed scaffold with carbohydrate based self-healing interpenetrating network (IPN)...

journal_title：International journal of biological macromolecules

authors： Gupta S,Sharma A,Vasantha Kumar J,Sharma V,Gupta PK,Verma RS

更新日期：2020-11-01 00:00:00

abstract：:This study focused on the investigation of bacterial cellulose production potency of some fruit and vegetable peels (cucumber, melon, kiwifruit, tomato, apple, quince and pomegranate) with Komagataeibacter hansenii GA2016. Fruit and vegetable peels were hydrolyzed, used for bacterial cellulose (BC) production and thei...

journal_title：International journal of biological macromolecules

authors： Güzel M,Akpınar Ö

更新日期：2020-11-01 00:00:00

abstract：:Here, we fabricated thermosensitive injectable hydrogel containing poly (N-isopropylacrylamide) (PNIPAAm)-based copolymer/graphene oxide (GO) composite with different feed ratio to chitosan (CS) as a natural polymer through physical and chemical crosslinking for the proliferation and differentiation of the human denta...

journal_title：International journal of biological macromolecules

authors： Amiryaghoubi N,Noroozi Pesyan N,Fathi M,Omidi Y

更新日期：2020-11-01 00:00:00

abstract：:The most critical issues faced by the world nowadays is to provide the sustainability of consumption for energy and natural resources. Lignin is said to be one of the alternative new discoveries best-suited lignocellulosic biomass due to its low cost, sufficient availability and environmentally safe. The valuable prop...

journal_title：International journal of biological macromolecules

authors： Liao JJ,Latif NHA,Trache D,Brosse N,Hussin MH

更新日期：2020-11-01 00:00:00

abstract：:In this work, we prepared novel cellulosic paper by incorporating tannin into the kraft pulp for potential application in active food packaging. The kraft pulp fibers were firstly periodate oxidized to obtain the dialdehyde cellulosic fibers, and then reacted with varied dosages of tannin to incorporate them into the ...

journal_title：International journal of biological macromolecules

authors： Ji Y,Xu Q,Jin L,Fu Y

更新日期：2020-11-01 00:00:00

abstract：:This study aimed to investigate the protective effects of walnut green husk polysaccharide (WGHP) on liver injury, vascular endothelial dysfunction and disorder of gut microbiota in mice induced by high fructose (HF) diet. The chemical analysis results show that the walnut green husk polysaccharide is a low molecular ...

journal_title：International journal of biological macromolecules

authors： Wang G,Zhang Y,Zhang R,Pan J,Qi D,Wang J,Yang X

更新日期：2020-11-01 00:00:00

abstract：:Breast cancer (BC) is among the leading causes of mortality from cancer in women. Many of the available anticancer drugs have various side effects. Therefore, researchers are seeking novel anticancer agents particularly from natural compounds and in this regard, snake venom is still one of the main sources of drug dis...

journal_title：International journal of biological macromolecules

authors： Derakhshani A,Silvestris N,Hajiasgharzadeh K,Mahmoudzadeh S,Fereidouni M,Paradiso AV,Brunetti O,Atarod D,Safarpour H,Baradaran B

更新日期：2020-11-01 00:00:00

abstract：:The present study addresses the immobilization of the GOX enzyme into a conventional polyvinyl alcohol (PVOH) membrane and a multi-layer membrane system (PCL/PVOH/PCL), both synthetized through electrospinning technique. More specifically, the enzyme was encapsulated inside a PVOH hydrophilic membrane, which was in tu...

journal_title：International journal of biological macromolecules

authors： Alonso-González M,Corral-González A,Felix M,Romero A,Martin-Alfonso JE

更新日期：2020-11-01 00:00:00

abstract：:In the present study, the influence of different concentrations of three fatty acids (palmitic, stearic, and oleic acids) on improving the physicochemical, barrier, mechanical, thermal and surface properties of Salvia macrosiphon seed gum (SSG) edible films was investigated. The results revealed that the selected fatt...

journal_title：International journal of biological macromolecules

authors： Amini AM,Razavi SMA

更新日期：2020-11-01 00:00:00

abstract：:Poly (lactic acid)-based functional films incorporated with curcumin have been prepared using a solution casting method. The PLA/curcumin composite film was flexible and highly transparent with bright yellow color. Curcumin was uniformly dispersed in the PLA matrix and showed excellent compatibility with PLA, as evide...

journal_title：International journal of biological macromolecules

authors： Roy S,Rhim JW

更新日期：2020-11-01 00:00:00

abstract：:Starch and derivatives thereof have proven their usefulness in paper coating processes. Among these derivatives, cationic starch has been widely used in the paper industry as a flocculation, dispersion and ink fixing agent. In another context, nanoscale cellulosic materials have been shown to improve the strength, ret...

journal_title：International journal of biological macromolecules

authors： Sharma M,Aguado R,Murtinho D,Valente AJM,Mendes De Sousa AP,Ferreira PJT

更新日期：2020-11-01 00:00:00

abstract：:This review aims to highlight the bioprocessing strategies behind one of the most commercially produced enzymes in the biotechnological market, pectinase. Significant steps in the upstream processing of this enzyme include its source, the selection of the substrate, the reaction conditions and the overall reactor desi...

journal_title：International journal of biological macromolecules

authors： John J,Kaimal KKS,Smith ML,Rahman PKSM,Chellam PV

更新日期：2020-11-01 00:00:00

abstract：:Nepetalactol, an iridoid with four chiral carbons, is a crucial component of aphid sex pheromones that have been employed with great success to control the insect-related diseases. Despite of agricultural usage as end products, iridoids are fundamental biosynthetic intermediates for pharmaceutically important monoterp...

journal_title：International journal of biological macromolecules

authors： Awadasseid A,Li W,Liu Z,Qiao C,Pang J,Zhang G,Luo Y

更新日期：2020-11-01 00:00:00

abstract：:The purposes of this study were to develop stable thyme essential oil chitosan nanoemulsions (TEO-CSs) and thymol chitosan nanoemulsions (T-CSs), and to evaluate their characterization and antibacterial properties. The effects of the TEO-CSs and T-CSs on preservation of refrigerated pork at 4 °C were also assessed. Th...

journal_title：International journal of biological macromolecules

authors： Liu T,Liu L

更新日期：2020-11-01 00:00:00

abstract：:Ethanol is currently the most successful biofuel and can be produced from microalgal biomass (third-generation). Ethanol from microalgal biomass has advantages because it does not use arable land and reduces environmental impacts through the sequestration of CO2 from the atmosphere. In this way, micro and macroalgal s...

journal_title：International journal of biological macromolecules

authors： da Maia JL,Cardoso JS,da Silveira Mastrantonio DJ,Bierhals CK,Moreira JB,Costa JAV,de Morais MG

更新日期：2020-10-23 00:00:00

abstract：:Broadband dielectric spectroscopy was used to investigate the molecular α-relaxation of the exopolysaccharides (EPS) extracted from Nostoc commune cyanobacteria. The EPS were modified in different ways. EPS were carboxymethylated to obtain carboxymethyl-exopolysaccharides (CEPS). EPS and CEPS were doped with ammonium ...

journal_title：International journal of biological macromolecules

authors： Gonzales KN,Troncoso OP,Torres FG,López D

更新日期：2020-10-15 00:00:00

abstract：:EPPS, a new heteropolysaccharide from Echinops pungens roots, was extracted by warm water (70 °C) and fortuitously purified using column chromatographies on DEAE-cellulose A52 and Sephadex G-100. Total carbohydrate content, specific optical rotation and molecular mass of EPPS were 98.3%, -88.2 and 65.7 kDa, respective...

journal_title：International journal of biological macromolecules

authors： Hoseiniyan Benvidi SM,Jahanbin K

更新日期：2020-10-15 00:00:00

abstract：:Carboxymethyl cellulose (CMC)/pPoly-N-isopropylacrylamide (PNIPAM) hydrogels were prepared using nanoclay as physical cross-linker by UV irradiation. PNIPAM/CMC hydrogels exhibit 3D network structures with high porosity. PNIPAM/CMC hydrogels exhibit not only high water absorption capacity, but also temperature, pH and...

journal_title：International journal of biological macromolecules

authors： Su C,Liu J,Yang Z,Jiang L,Liu X,Shao W

更新日期：2020-10-15 00:00:00

abstract：:Conceivably the imperative reason for the absence of appropriate treatment for Alzheimer's disease (AD) is the late onset of clinical symptoms followed by late treatment. Specific biomarkers play a vital role in this area. The amyloid-beta peptide, tau protein and micRNA, are the most important biomarker associated in...

journal_title：International journal of biological macromolecules

authors： Mobed A,Hasanzadeh M

更新日期：2020-10-15 00:00:00

abstract：:Heparan sulfate (HS) is a linear anionic polysaccharide with repeating sulfated disaccharide units, which has been proven with various regulatory osteogenesis effects through multi-pathway signaling, but its impacts on receptor-activator of nuclear factor kappa beta ligand/receptor-activator of nuclear factor kappa be...

journal_title：International journal of biological macromolecules

authors： Liu Y,Xu Z,Wang Q,Jiang Y,Wang R,Chen S,Zhu J,Zhang Y,Chen J

更新日期：2020-10-15 00:00:00